Endoscopic management of refractory benign oesophageal strictures

Endoscopic management of refractory benign oesophageal strictures

Refractory benign oesophageal strictures are an infrequent presentation but a cause of significant morbidity and mortality. The treatment of these strictures has changed little in recent years, yet new evidence is emerging for the optimal timing and application of different therapies. In this articl...

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Main Author: Simon M. Everett
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Therapeutic Advances in Gastrointestinal Endoscopy
Online Access:https://doi.org/10.1177/2631774519862134
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spelling doaj-4c8b562c5637443b8056dbc05159cf892020-11-25T03:48:29ZengSAGE PublishingTherapeutic Advances in Gastrointestinal Endoscopy2631-77452019-07-011210.1177/2631774519862134Endoscopic management of refractory benign oesophageal stricturesSimon M. EverettRefractory benign oesophageal strictures are an infrequent presentation but a cause of significant morbidity and mortality. The treatment of these strictures has changed little in recent years, yet new evidence is emerging for the optimal timing and application of different therapies. In this article, we have carefully reviewed the current literature on the evaluation and management of refractory strictures and provided practical advice as to their management. A number of areas require attention in future research, including carefully designed randomised trials of endoscopic and medical therapies, and a focus on risk factors at a patient and molecular level to facilitate development of medical therapies that can reduce recurrent fibrosis in these patients.https://doi.org/10.1177/2631774519862134
collection DOAJ
language English
format Article
sources DOAJ
author Simon M. Everett
spellingShingle Simon M. Everett
Endoscopic management of refractory benign oesophageal strictures
Therapeutic Advances in Gastrointestinal Endoscopy
author_facet Simon M. Everett
author_sort Simon M. Everett
title Endoscopic management of refractory benign oesophageal strictures
title_short Endoscopic management of refractory benign oesophageal strictures
title_full Endoscopic management of refractory benign oesophageal strictures
title_fullStr Endoscopic management of refractory benign oesophageal strictures
title_full_unstemmed Endoscopic management of refractory benign oesophageal strictures
title_sort endoscopic management of refractory benign oesophageal strictures
publisher SAGE Publishing
series Therapeutic Advances in Gastrointestinal Endoscopy
issn 2631-7745
publishDate 2019-07-01
description Refractory benign oesophageal strictures are an infrequent presentation but a cause of significant morbidity and mortality. The treatment of these strictures has changed little in recent years, yet new evidence is emerging for the optimal timing and application of different therapies. In this article, we have carefully reviewed the current literature on the evaluation and management of refractory strictures and provided practical advice as to their management. A number of areas require attention in future research, including carefully designed randomised trials of endoscopic and medical therapies, and a focus on risk factors at a patient and molecular level to facilitate development of medical therapies that can reduce recurrent fibrosis in these patients.
url https://doi.org/10.1177/2631774519862134
work_keys_str_mv AT simonmeverett endoscopicmanagementofrefractorybenignoesophagealstrictures
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