Whole blood mRNA expression-based targets to discriminate active tuberculosis from latent infection and other pulmonary diseases

Abstract Current diagnostic tests for tuberculosis (TB) are not able to predict reactivation disease progression from latent TB infection (LTBI). The main barrier to predicting reactivation disease is the lack of our understanding of host biomarkers associated with progression from latent infection...

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Bibliographic Details
Main Authors: Jéssica D. Petrilli, Luana E. Araújo, Luciane Sussuchi da Silva, Ana Carolina Laus, Igor Müller, Rui Manuel Reis, Eduardo Martins Netto, Lee W. Riley, Sérgio Arruda, Adriano Queiroz
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78793-2