Roles of A-Kinase Anchoring Proteins and Phosphodiesterases in the Cardiovascular System
A-kinase anchoring proteins (AKAPs) and cyclic nucleotide phosphodiesterases (PDEs) are essential enzymes in the cyclic adenosine 3’-5’ monophosphate (cAMP) signaling cascade. They establish local cAMP pools by controlling the intensity, duration and compartmentalization of cyclic nucleotide-depende...
Main Authors: | Maria Ercu, Enno Klussmann |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
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Series: | Journal of Cardiovascular Development and Disease |
Subjects: | |
Online Access: | http://www.mdpi.com/2308-3425/5/1/14 |
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