Control of Gene Expression by RNA Binding Protein Action on Alternative Translation Initiation Sites.

Control of Gene Expression by RNA Binding Protein Action on Alternative Translation Initiation Sites.

Transcript levels do not faithfully predict protein levels, due to post-transcriptional regulation of gene expression mediated by RNA binding proteins (RBPs) and non-coding RNAs. We developed a multivariate linear regression model integrating RBP levels and predicted RBP-mRNA regulatory interactions...

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Bibliographic Details
Main Authors: Angela Re, Levi Waldron, Alessandro Quattrone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5140048?pdf=render

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