The Role of MR Mammography in Differentiating Benign from Malignant in Suspicious Breast Masses
Introduction: Magnetic Resonance (MR) Mammography is being increasingly used now-a-days for the evaluation of breast lesions. Aim: To find out the effectiveness and the exact role of MR mammography in differentiating benign lesions from malignant lesions in patients with palpable, suspicious br...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2016-09-01
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Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/8456/21820_CE[Ra1]_F(GH)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
Summary: | Introduction: Magnetic Resonance (MR) Mammography is
being increasingly used now-a-days for the evaluation of breast
lesions.
Aim: To find out the effectiveness and the exact role of MR
mammography in differentiating benign lesions from malignant
lesions in patients with palpable, suspicious breast masses
found on routine conventional imaging techniques.
Materials and Methods: It was a prospective study wherein
patients with suspicious breast lesions were subjected to MR
mammography. The morphological feature (smooth vs irregular
margin) and the enhancement patterns (Type Ia/Ib vs Type II vs
Type III) of the lesions were assessed and finally the effectiveness
of MR mammography in differentiating benign and malignant
lesions was judged by taking the histopathological diagnosis as
the gold standard.
Results: A total of 33 patients with 35 breast lesions were finally
analysed. The sensitivity, specificity, Positive Predictive Value
(PPV) and the Negative Predictive Value (NPV) in differentiating
benign from malignant breast lesion for the type of margin on
MR mammography was 95.45%, 84.6%, 91.3% and 91.7%,
while for the type of enhancement curve it was 76.2%, 90.9%,
94.1% and 66.7% respectively. The sensitivity and negative
predictive value for the type of margins was statistically
better when compared to the type of enhancement curve in
differentiating benign from malignant lesions but the specificity
and PPV though better for the type of enhancement curve was
not found to be statistically significant.
Conclusion: MR mammography was found to be an effective
tool in differentiating benign from malignant suspicious breast
lesions. The type of margin and the enhancement patterns both
individually and in combination provide the clinicians with ample
information so as to decide on further management. |
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ISSN: | 2249-782X 0973-709X |