The role of G protein gene <it>GNB3 C825T </it>Polymorphism in HIV-1 acquisition, progression and immune activation

The role of G protein gene <it>GNB3 C825T </it>Polymorphism in HIV-1 acquisition, progression and immune activation

<p>Abstract</p> <p>Background</p> <p>The <it>GNB3 C825T </it>polymorphism is associated with increased G protein-mediated signal transduction, SDF-1α-mediated lymphocyte chemotaxis, accelerated HIV-1 progression, and altered responses to antiretroviral thera...

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Bibliographic Details
Main Authors: Juno Jennifer, Tuff Jeffrey, Choi Robert, Card Catherine, Kimani Joshua, Wachihi Charles, Koesters-Kiazyk Sandra, Ball T Blake, Farquhar Carey, Plummer Francis A, John-Stewart Grace, Luo Ma, Fowke Keith R
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Retrovirology
Subjects:
GNB3
HIV progression
G protein
HIV acquisition
Immune Activation
Online Access:http://www.retrovirology.com/content/9/1/1

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