Conditional Knockdown of Osteopontin Inhibits Breast Cancer Skeletal Metastasis
High osteopontin (OPN) expression is linked to breast cancer bone metastasis. In this study we modulated osteopontin levels conditionally and investigated any related antineoplastic effects. Therefore, we established cell clones from human breast cancer MDA-MB-231 cells, in which the expression of O...
Main Authors: | Marineta Kovacheva, Michael Zepp, Muriel Schraad, Stefan Berger, Martin R. Berger |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/19/4918 |
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