Graded Maximal Exercise Testing to Assess Mouse Cardio-Metabolic Phenotypes.

Functional assessments of cardiovascular fitness (CVF) are needed to establish animal models of dysfunction, test the effects of novel therapeutics, and establish the cardio-metabolic phenotype of mice. In humans, the graded maximal exercise test (GXT) is a standardized diagnostic for assessing CVF...

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Bibliographic Details
Main Authors: Jennifer M Petrosino, Valerie J Heiss, Santosh K Maurya, Anuradha Kalyanasundaram, Muthu Periasamy, Richard A LaFountain, Jacob M Wilson, Orlando P Simonetti, Ouliana Ziouzenkova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4747552?pdf=render