Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas

Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas

BackgroundShort telomere length (TL) is associated with age-related diseases, in particular cardiovascular diseases. However, whether the onset and course of aortic stenosis (AS) is linked to TL in aortic valves remains unknown.ObjectivesTo assess telomere dynamics (TL and telomerase activity) in ao...

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Bibliographic Details
Main Authors: Ilona Saraieva, Athanase Benetos, Carlos Labat, Anders Franco-Cereceda, Magnus Bäck, Simon Toupance
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
telomere length
aortic valve
aortic stenosis
calcification
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.618335/full

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