Origin of secretin receptor precedes the advent of tetrapoda: evidence on the separated origins of secretin and orexin.

Origin of secretin receptor precedes the advent of tetrapoda: evidence on the separated origins of secretin and orexin.

At present, secretin and its receptor have only been identified in mammals, and the origin of this ligand-receptor pair in early vertebrates is unclear. In addition, the elusive similarities of secretin and orexin in terms of both structures and functions suggest a common ancestral origin early in t...

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Bibliographic Details
Main Authors: Janice K V Tam, Kwan-Wa Lau, Leo T O Lee, Jessica Y S Chu, Kwong-Man Ng, Alain Fournier, Hubert Vaudry, Billy K C Chow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084839?pdf=render

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http://europepmc.org/articles/PMC3084839?pdf=render

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