Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.
Main Authors: | Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Bénédicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Françoise Bachelerie, Olivier Schwartz, Jan Münch, Andreas Wack, Sébastien Nisole, Jean-Philippe Herbeuval |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms14253 |
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