Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease
Squamous cell carcinoma (SCC) of the endometrium, whether primary or secondary to cervical cancer, is a rare entity. Primary endometrial squamous cell carcinoma in situ is even more uncommon; it usually occurs in postmenopausal women and has a strong association with pyometra. We report a 60-year-...
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doaj-4dd7ed22a85042f4a68feaa6f8f8a6d42020-11-24T21:44:52ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal 2075-051X2075-05282015-11-01154e55956210.18295/squmj.2015.15.04.021Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare diseaseSujata Jetley0Zeeba S. Jairajpuri1Mohammad J. Hassan2Garima Madaan3Reena Jain4Department of Pathology, Hamdard Institute of Medical Sciences & Research, New Delhi, IndiaDepartment of Pathology, Hamdard Institute of Medical Sciences & Research, New Delhi, IndiaDepartment of Pathology, Hamdard Institute of Medical Sciences & Research, New Delhi, IndiaDepartment of Pathology, Hamdard Institute of Medical Sciences & Research, New Delhi, IndiaDepartment of Obstetrics & Gynaecology, Hamdard Institute of Medical Sciences & Research, New Delhi, IndiaSquamous cell carcinoma (SCC) of the endometrium, whether primary or secondary to cervical cancer, is a rare entity. Primary endometrial squamous cell carcinoma in situ is even more uncommon; it usually occurs in postmenopausal women and has a strong association with pyometra. We report a 60-year-old multiparous postmenopausal woman who presented to the Hakeem Abdul Hameed Centenary Hospital, New Delhi, India, in May 2014 with a lower abdominal swelling corresponding in size to a pregnancy of 26 gestational weeks and vaginal discharge of one year’s duration. A total abdominal hysterectomy with a bilateral salpingooophorectomy was performed, which revealed an enlarged uterus with pyometra. Histopathology showed that the entire endometrial lining had been replaced with malignant squamous cells without invasion of the myometrium. Immunohistochemistry revealed that the tumour cells were positive for p63 with a high Ki-67 labelling index. No adjuvant therapy was required and the patient was disease-free at a seven-month follow-up.http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=98f007e379bd613fe8841a5a1611f6c7Squamous Cell CarcinomaEndometriumPyometraCase ReportIndia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sujata Jetley Zeeba S. Jairajpuri Mohammad J. Hassan Garima Madaan Reena Jain |
spellingShingle |
Sujata Jetley Zeeba S. Jairajpuri Mohammad J. Hassan Garima Madaan Reena Jain Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease Sultan Qaboos University Medical Journal Squamous Cell Carcinoma Endometrium Pyometra Case Report India |
author_facet |
Sujata Jetley Zeeba S. Jairajpuri Mohammad J. Hassan Garima Madaan Reena Jain |
author_sort |
Sujata Jetley |
title |
Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease |
title_short |
Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease |
title_full |
Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease |
title_fullStr |
Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease |
title_full_unstemmed |
Primary Endometrial Squamous Cell Carcinoma In Situ; Report of a rare disease |
title_sort |
primary endometrial squamous cell carcinoma in situ; report of a rare disease |
publisher |
Sultan Qaboos University |
series |
Sultan Qaboos University Medical Journal |
issn |
2075-051X 2075-0528 |
publishDate |
2015-11-01 |
description |
Squamous cell carcinoma (SCC) of the endometrium, whether primary or secondary to cervical
cancer, is a rare entity. Primary endometrial squamous cell carcinoma in situ is even more uncommon; it
usually occurs in postmenopausal women and has a strong association with pyometra. We report a 60-year-old
multiparous postmenopausal woman who presented to the Hakeem Abdul Hameed Centenary Hospital, New
Delhi, India, in May 2014 with a lower abdominal swelling corresponding in size to a pregnancy of 26 gestational
weeks and vaginal discharge of one year’s duration. A total abdominal hysterectomy with a bilateral salpingooophorectomy
was performed, which revealed an enlarged uterus with pyometra. Histopathology showed that the
entire endometrial lining had been replaced with malignant squamous cells without invasion of the myometrium.
Immunohistochemistry revealed that the tumour cells were positive for p63 with a high Ki-67 labelling index. No
adjuvant therapy was required and the patient was disease-free at a seven-month follow-up. |
topic |
Squamous Cell Carcinoma Endometrium Pyometra Case Report India |
url |
http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=98f007e379bd613fe8841a5a1611f6c7 |
work_keys_str_mv |
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