Small RNA Plays Important Roles in Virus–Host Interactions

Non-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA...

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Main Authors: Hui Dai, Weifeng Gu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/11/1271
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spelling doaj-4de8a1679cea47d48d6af146e8075b012020-11-25T04:08:31ZengMDPI AGViruses1999-49152020-11-01121271127110.3390/v12111271Small RNA Plays Important Roles in Virus–Host InteractionsHui Dai0Weifeng Gu1Department of Molecular, Cell and Systems Biology, University of California, Riverside 900 University Avenue, Riverside, CA 92521, USADepartment of Molecular, Cell and Systems Biology, University of California, Riverside 900 University Avenue, Riverside, CA 92521, USANon-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA mediated virus–host interactions, and focuses on influenza virus cap-snatching and a few important virus sensors including PIR-1, RIG-I like protein DRH-1 and piRNAs. The paper also discusses recent advances in mammalian antiviral RNAi.https://www.mdpi.com/1999-4915/12/11/1271virus–host interactionnon-coding small RNAsantivirusRNAiRNA phosphatase
collection DOAJ
language English
format Article
sources DOAJ
author Hui Dai
Weifeng Gu
spellingShingle Hui Dai
Weifeng Gu
Small RNA Plays Important Roles in Virus–Host Interactions
Viruses
virus–host interaction
non-coding small RNAs
antivirus
RNAi
RNA phosphatase
author_facet Hui Dai
Weifeng Gu
author_sort Hui Dai
title Small RNA Plays Important Roles in Virus–Host Interactions
title_short Small RNA Plays Important Roles in Virus–Host Interactions
title_full Small RNA Plays Important Roles in Virus–Host Interactions
title_fullStr Small RNA Plays Important Roles in Virus–Host Interactions
title_full_unstemmed Small RNA Plays Important Roles in Virus–Host Interactions
title_sort small rna plays important roles in virus–host interactions
publisher MDPI AG
series Viruses
issn 1999-4915
publishDate 2020-11-01
description Non-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA mediated virus–host interactions, and focuses on influenza virus cap-snatching and a few important virus sensors including PIR-1, RIG-I like protein DRH-1 and piRNAs. The paper also discusses recent advances in mammalian antiviral RNAi.
topic virus–host interaction
non-coding small RNAs
antivirus
RNAi
RNA phosphatase
url https://www.mdpi.com/1999-4915/12/11/1271
work_keys_str_mv AT huidai smallrnaplaysimportantrolesinvirushostinteractions
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