Characterization of UMi031-A-2 inducible pluripotent stem cell line with a neurofibromatosis type 2-associated mutation

Characterization of UMi031-A-2 inducible pluripotent stem cell line with a neurofibromatosis type 2-associated mutation

The UMi031-A-2 hiPSC line contains a CRISPR-induced homozygous, Neurofibromatosis Type 2 (NF2) mutation (L64P (CTG > CCG)) in the NF2 gene that encodes a merlin tumor suppressor. This line was generated from an unaffected iPSC line using CRISPR technology and characterized for pluripotency and ka...

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Bibliographic Details
Main Authors:	Aida Nourbakhsh, Nicholas C. Gosstola, Cristina Fernandez-Valle, Derek M. Dykxhoorn, Xue Zhong Liu
Format:	Article
Language:	English
Published:	Elsevier 2021-08-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506121003214

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