pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivo
Abstract Background Mesenchymal/stromal stem cells (MSCs) are favorably regarded in anti-cancer cytotherapies for their spontaneous chemotaxis toward inflammatory and tumor environments associated with an intrinsic cytotoxicity against tumor cells. Placenta-derived or TRAIL-engineered adipose MSCs h...
Main Authors: | Paola Cafforio, Luigi Viggiano, Francesco Mannavola, Eleonora Pellè, Concetta Caporusso, Eugenio Maiorano, Claudia Felici, Francesco Silvestris |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13287-017-0655-6 |
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