In Vivo Brain Imaging, Biodistribution, and Radiation Dosimetry Estimation of [11C]Celecoxib, a COX-2 PET Ligand, in Nonhuman Primates

In Vivo Brain Imaging, Biodistribution, and Radiation Dosimetry Estimation of [11C]Celecoxib, a COX-2 PET Ligand, in Nonhuman Primates

COX-2 selective inhibitors (COXIBs) are non-steroidal anti-inflammatory drugs (NSAIDs), with fewer side effects compared with non-selective NSAIDs, and are used for the treatment of arthritis, headaches, and other inflammatory diseases of the brain and peripheral tissues. Radiolabeled COXIBs may per...

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Bibliographic Details
Main Authors: J. S. Dileep Kumar, Bing Bai, Francesca Zanderigo, Christine DeLorenzo, Jaya Prabhakaran, Ramin V. Parsey, J. John Mann
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
PET
COX-2
celecoxib
dosimetry
biodistribution
brain
Online Access:http://www.mdpi.com/1420-3049/23/8/1929

Internet

http://www.mdpi.com/1420-3049/23/8/1929

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