A1C Underperforms as a Diagnostic Test in Africans Even in the Absence of Nutritional Deficiencies, Anemia and Hemoglobinopathies: Insight From the Africans in America Study

A1C Underperforms as a Diagnostic Test in Africans Even in the Absence of Nutritional Deficiencies, Anemia and Hemoglobinopathies: Insight From the Africans in America Study

Introduction: To improve detection of undiagnosed diabetes in Africa, there is movement to replace the OGTT with A1C. The performance of A1C in the absence of hemoglobin-related micronutrient deficiencies, anemia and heterozygous hemoglobinopathies is unknown. Therefore, we determined in 441 African...

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Bibliographic Details
Main Authors: Sara M. Briker, Jessica Y. Aduwo, Regine Mugeni, Margrethe F. Horlyck-Romanovsky, Christopher W. DuBose, Lilian S. Mabundo, Thomas Hormenu, Stephanie T. Chung, Joon Ha, Arthur Sherman, Anne E. Sumner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Endocrinology
Subjects:
diabetes
Africans
sickle cell trait
anemia
A1C
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00533/full

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