Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans
A total of 272 methicillin-resistant Staphylococcus aureus (MRSA) from equine infections originating from 17 equine hospitals and 39 veterinary practices in Germany as well as 67 isolates from personnel working at equine clinics were subjected to molecular typing. The majority of isolates from horse...
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doaj-4e2ddd364f494a468af3457262ef4bdd2020-11-24T22:58:43ZengElsevierOne Health2352-77142016-12-012C111710.1016/j.onehlt.2015.11.004Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humansChristiane Cuny0Mohamed M.H. Abdelbary1Robin Köck2Franziska Layer3Wolfgang Scheidemann4Guido Werner5Wolfgang Witte6Robert Koch-Institute, German Reference Center for Staphylococci and Enterococci, Wernigerode, Burgstraße 37, 38855 Wernigerode, GermanyRobert Koch-Institute, German Reference Center for Staphylococci and Enterococci, Wernigerode, Burgstraße 37, 38855 Wernigerode, GermanyInstitute of Medical Microbiology, University Hospital Münster, Domagkstraße 10, 48149 Münster, GermanyRobert Koch-Institute, German Reference Center for Staphylococci and Enterococci, Wernigerode, Burgstraße 37, 38855 Wernigerode, GermanyTierärztliche Klinik für Pferde, Domäne Karthaus, Weddern 16c, 48249 Dülmen Dülmen, GermanyRobert Koch-Institute, German Reference Center for Staphylococci and Enterococci, Wernigerode, Burgstraße 37, 38855 Wernigerode, GermanyRobert Koch-Institute, German Reference Center for Staphylococci and Enterococci, Wernigerode, Burgstraße 37, 38855 Wernigerode, GermanyA total of 272 methicillin-resistant Staphylococcus aureus (MRSA) from equine infections originating from 17 equine hospitals and 39 veterinary practices in Germany as well as 67 isolates from personnel working at equine clinics were subjected to molecular typing. The majority of isolates from horses was attributed to clonal complex (CC) 398 (82.7%). Within CC398, 66% of isolates belonged to a subpopulation (clade) of CC398, which is associated with equine clinics. MRSA attributed to CC8 (ST254, t009, t036, SCCmecIV; ST8, t064, SCCmecIV) were less frequent (16.5%). Single isolates were attributed to ST1, CC22, ST130, and ST1660. The emergence of MRSA CC22 and ST130 in horses was not reported so far. Nasal MRSA colonization was found in 19.5% of veterinary personnel with occupational exposure to horses. The typing characteristics of these isolates corresponded to isolates from equine infections. Comparing typing characteristics of equine isolates with those of a substantial number of isolates from human infections typed at the German Reference Center for Staphylococci and Enterococci (2006–2014; n = 10864) yielded that the proportion of isolates exhibiting characteristics of MRSA from equine medicine is very low (<0.5%). As this low proportion was also found among MRSA originating from nasal screenings of human carriers not suffering from a staphylococcal infection (n = 5546) transmission of MRSA from equine clinics to the community seems to be rare so far.http://www.sciencedirect.com/science/article/pii/S2352771415000142MRSAEquine clinic associated MRSAZoonotic transmissionHost specificity |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christiane Cuny Mohamed M.H. Abdelbary Robin Köck Franziska Layer Wolfgang Scheidemann Guido Werner Wolfgang Witte |
spellingShingle |
Christiane Cuny Mohamed M.H. Abdelbary Robin Köck Franziska Layer Wolfgang Scheidemann Guido Werner Wolfgang Witte Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans One Health MRSA Equine clinic associated MRSA Zoonotic transmission Host specificity |
author_facet |
Christiane Cuny Mohamed M.H. Abdelbary Robin Köck Franziska Layer Wolfgang Scheidemann Guido Werner Wolfgang Witte |
author_sort |
Christiane Cuny |
title |
Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans |
title_short |
Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans |
title_full |
Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans |
title_fullStr |
Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans |
title_full_unstemmed |
Methicillin-resistant Staphylococcus aureus from infections in horses in Germany are frequent colonizers of veterinarians but rare among MRSA from infections in humans |
title_sort |
methicillin-resistant staphylococcus aureus from infections in horses in germany are frequent colonizers of veterinarians but rare among mrsa from infections in humans |
publisher |
Elsevier |
series |
One Health |
issn |
2352-7714 |
publishDate |
2016-12-01 |
description |
A total of 272 methicillin-resistant Staphylococcus aureus (MRSA) from equine infections originating from 17 equine hospitals and 39 veterinary practices in Germany as well as 67 isolates from personnel working at equine clinics were subjected to molecular typing. The majority of isolates from horses was attributed to clonal complex (CC) 398 (82.7%). Within CC398, 66% of isolates belonged to a subpopulation (clade) of CC398, which is associated with equine clinics.
MRSA attributed to CC8 (ST254, t009, t036, SCCmecIV; ST8, t064, SCCmecIV) were less frequent (16.5%). Single isolates were attributed to ST1, CC22, ST130, and ST1660. The emergence of MRSA CC22 and ST130 in horses was not reported so far. Nasal MRSA colonization was found in 19.5% of veterinary personnel with occupational exposure to horses. The typing characteristics of these isolates corresponded to isolates from equine infections.
Comparing typing characteristics of equine isolates with those of a substantial number of isolates from human infections typed at the German Reference Center for Staphylococci and Enterococci (2006–2014; n = 10864) yielded that the proportion of isolates exhibiting characteristics of MRSA from equine medicine is very low (<0.5%). As this low proportion was also found among MRSA originating from nasal screenings of human carriers not suffering from a staphylococcal infection (n = 5546) transmission of MRSA from equine clinics to the community seems to be rare so far. |
topic |
MRSA Equine clinic associated MRSA Zoonotic transmission Host specificity |
url |
http://www.sciencedirect.com/science/article/pii/S2352771415000142 |
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