A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
Sepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing.
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Nature Publishing Group
2017-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15949 |
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doaj-4e330b972dd54f1d9071ee67fbca8cbe2021-05-11T07:10:48ZengNature Publishing GroupNature Communications2041-17232017-07-018111210.1038/ncomms15949A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratificationU. Hassan0T. Ghonge1B. Reddy Jr.2M. Patel3M. Rappleye4I. Taneja5A. Tanna6R. Healey7N. Manusry8Z. Price9T. Jensen10J. Berger11A. Hasnain12E. Flaugher13S. Liu14B. Davis15J. Kumar16K. White17R. Bashir18Department of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignMicro and Nanotechnology Lab, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignBiomedical Research Center, Carle Foundation HospitalDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignDepartment of Bioengineering, University of Illinois at Urbana-ChampaignBiomedical Research Center, Carle Foundation HospitalBiomedical Research Center, Carle Foundation HospitalBiomedical Research Center, Carle Foundation HospitalDepartment of Bioengineering, University of Illinois at Urbana-ChampaignSepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing.https://doi.org/10.1038/ncomms15949 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
U. Hassan T. Ghonge B. Reddy Jr. M. Patel M. Rappleye I. Taneja A. Tanna R. Healey N. Manusry Z. Price T. Jensen J. Berger A. Hasnain E. Flaugher S. Liu B. Davis J. Kumar K. White R. Bashir |
| spellingShingle |
U. Hassan T. Ghonge B. Reddy Jr. M. Patel M. Rappleye I. Taneja A. Tanna R. Healey N. Manusry Z. Price T. Jensen J. Berger A. Hasnain E. Flaugher S. Liu B. Davis J. Kumar K. White R. Bashir A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification Nature Communications |
| author_facet |
U. Hassan T. Ghonge B. Reddy Jr. M. Patel M. Rappleye I. Taneja A. Tanna R. Healey N. Manusry Z. Price T. Jensen J. Berger A. Hasnain E. Flaugher S. Liu B. Davis J. Kumar K. White R. Bashir |
| author_sort |
U. Hassan |
| title |
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification |
| title_short |
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification |
| title_full |
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification |
| title_fullStr |
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification |
| title_full_unstemmed |
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification |
| title_sort |
point-of-care microfluidic biochip for quantification of cd64 expression from whole blood for sepsis stratification |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-07-01 |
| description |
Sepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing. |
| url |
https://doi.org/10.1038/ncomms15949 |
| work_keys_str_mv |
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