New Insights in the Pathogenesis of Multiple Sclerosis—Role of Acrolein in Neuronal and Myelin Damage

New Insights in the Pathogenesis of Multiple Sclerosis—Role of Acrolein in Neuronal and Myelin Damage

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by an inappropriate inflammatory reaction resulting in widespread myelin injury along white matter tracts. Neurological impairment as a result of the disease can be attributed to immune-mediated injury...

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Bibliographic Details
Main Authors: Riyi Shi, Melissa Tully
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
acrolein
oxidative stress
autoimmune
neurodegeneration
demyelination
axonal injury
EAE
hydralazine
Online Access:http://www.mdpi.com/1422-0067/14/10/20037

Internet

http://www.mdpi.com/1422-0067/14/10/20037

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