Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats

Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats

Neuroinflammation-related amyloid-beta peptide (Aβ) accumulation after cerebral ischemia/reperfusion (I/R) accounts for cerebral I/R injuries and poststroke dementia. Recently, pyroptosis, a proinflammatory cell death, has been identified as a crucial pathological link of cerebral I/R injuries. Howe...

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Bibliographic Details
Main Authors:	Zhongkuan Lyu, Yuanjin Chan, Qiyue Li, Qiang Zhang, Kaili Liu, Jun Xiang, Xiangting Li, Dingfang Cai, Yaming Li, Bing Wang, Zhonghai Yu
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Neural Plasticity
Online Access:	http://dx.doi.org/10.1155/2021/4504363

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