Preparation and purification of novel phosphatidyl prodrug and performance modulation of phosphatidyl nanoprodrug
Abstract Background A novel phosphatidyl nanoprodrug system can be selectively released parent drugs in cancer cells, triggered by the local overexpression of phospholipase D (PLD). This system significantly reduces the intrinsic disadvantages of conventional chemotherapeutic drugs. However, the sep...
Main Authors: | Rui Niu, PeiLei Zhang, Feng-Qing Wang, Min Liu, QingHai Liu, Ning Jia, ShengLi Yang, XinYi Tao, DongZhi Wei |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2019-11-01
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Series: | Bioresources and Bioprocessing |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40643-019-0277-1 |
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