Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost

Laparoscopic extraperitoneal radical prostatectomy (LERP) is considered the standard care treatment option for the management of localized and locally advanced prostatic cancer (PCa) in many institutes worldwide. In this work, the main advantages and disadvantages of LERP approach are reviewed with...

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Main Authors: Evangelos Liatsikos, Iason Kyriazis, Panagiotis Kallidonis, Minh Do, Tim Haefner, Anja Dietel, Sigrun Holze, Narasimhan Ragavan, Jens-Uwe Stolzenburg
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2011/150978
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spelling doaj-4e7d51aa895b4abf88bf22dfe9cfea8b2020-11-24T23:41:25ZengHindawi LimitedProstate Cancer2090-31112090-312X2011-01-01201110.1155/2011/150978150978Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is LostEvangelos Liatsikos0Iason Kyriazis1Panagiotis Kallidonis2Minh Do3Tim Haefner4Anja Dietel5Sigrun Holze6Narasimhan Ragavan7Jens-Uwe Stolzenburg8Department of Urology, University of Patras, Medical School, Rion, 26 500 Patras, GreeceDepartment of Urology, University of Patras, Medical School, Rion, 26 500 Patras, GreeceDepartment of Urology, University of Patras, Medical School, Rion, 26 500 Patras, GreeceDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyDepartment of Urology, University of Leipzig, 04109 Leipzig, GermanyLaparoscopic extraperitoneal radical prostatectomy (LERP) is considered the standard care treatment option for the management of localized and locally advanced prostatic cancer (PCa) in many institutes worldwide. In this work, the main advantages and disadvantages of LERP approach are reviewed with regard to its outcomes, the complication management, the learning curve, and the extend of pelvic lymph node dissection (PLND). It is concluded that LERP demonstrates comparable cancer control, urinary continence, and potency outcomes with the open and the robot-assisted radical prostatectomy, while offering advantages in complication management in comparison to the transperitoneal approach. Learning curve of LERP is considered long and stiff and significantly affects perioperative outcomes and morbidity, cancer control, and functional results. Thus, close mentoring especially in the beginning of the learning curve is advised. Finally, LERP still has a role in the limited or modified PLND offered in intermediate risk PCa patients.http://dx.doi.org/10.1155/2011/150978
collection DOAJ
language English
format Article
sources DOAJ
author Evangelos Liatsikos
Iason Kyriazis
Panagiotis Kallidonis
Minh Do
Tim Haefner
Anja Dietel
Sigrun Holze
Narasimhan Ragavan
Jens-Uwe Stolzenburg
spellingShingle Evangelos Liatsikos
Iason Kyriazis
Panagiotis Kallidonis
Minh Do
Tim Haefner
Anja Dietel
Sigrun Holze
Narasimhan Ragavan
Jens-Uwe Stolzenburg
Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
Prostate Cancer
author_facet Evangelos Liatsikos
Iason Kyriazis
Panagiotis Kallidonis
Minh Do
Tim Haefner
Anja Dietel
Sigrun Holze
Narasimhan Ragavan
Jens-Uwe Stolzenburg
author_sort Evangelos Liatsikos
title Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
title_short Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
title_full Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
title_fullStr Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
title_full_unstemmed Comments on the Extraperitoneal Approach for Standard Laparoscopic Radical Prostatectomy: What Is Gained and What Is Lost
title_sort comments on the extraperitoneal approach for standard laparoscopic radical prostatectomy: what is gained and what is lost
publisher Hindawi Limited
series Prostate Cancer
issn 2090-3111
2090-312X
publishDate 2011-01-01
description Laparoscopic extraperitoneal radical prostatectomy (LERP) is considered the standard care treatment option for the management of localized and locally advanced prostatic cancer (PCa) in many institutes worldwide. In this work, the main advantages and disadvantages of LERP approach are reviewed with regard to its outcomes, the complication management, the learning curve, and the extend of pelvic lymph node dissection (PLND). It is concluded that LERP demonstrates comparable cancer control, urinary continence, and potency outcomes with the open and the robot-assisted radical prostatectomy, while offering advantages in complication management in comparison to the transperitoneal approach. Learning curve of LERP is considered long and stiff and significantly affects perioperative outcomes and morbidity, cancer control, and functional results. Thus, close mentoring especially in the beginning of the learning curve is advised. Finally, LERP still has a role in the limited or modified PLND offered in intermediate risk PCa patients.
url http://dx.doi.org/10.1155/2011/150978
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