Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae
The amidotransferase MurT/GatD complex catalyzes peptidoglycan precursor amidation in some Gram-positive bacteria. Here the authors present the crystal structure of the Streptococcus pneumoniae MurT/GatD complex and provide mechanistic insights, which are of interest for drug development.
Bibliographic Details
| Main Authors: |
Cécile Morlot,
Daniel Straume,
Katharina Peters,
Olav A. Hegnar,
Nolwenn Simon,
Anne-Marie Villard,
Carlos Contreras-Martel,
Francisco Leisico,
Eefjan Breukink,
Christine Gravier-Pelletier,
Laurent Le Corre,
Waldemar Vollmer,
Nicolas Pietrancosta,
Leiv Sigve Håvarstein,
André Zapun |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-05602-w
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