Comparison of Coronary Artery Calcium Scores with Platelet Volume and Uric Acid Levels in Patients Who Underwent Coronary Artery Imaging with Computed Tomography

• Main Authors: Murat Bulunmaz, Metin Demir, Betül Börkü Uysal, Simge Erdem, Hayri Polat, Mecdi Hikmet Ergüney
• Format: Article
• Language: English
• Published: Galenos Yayinevi 2015-03-01
• Series: İstanbul Medical Journal
• Subjects: Coronary artery disease; coronary artery calcium score; mean platelet volume (MPV); uric acid; multidetector computed tomography (MDCT)
• Online Access: http://imj.galenos.com.tr/archives/archive-detail/article-preview/comparison-of-coronary-artery-calcium-scores-with-/21002

Objective: The aim of this study is to evaluate the association of coronary artery calcium score and the increased risk of coronary artery disease with mean platelet volume (MPV) and uric acid.Methods: For this retrospective study, patients with a preliminary diagnosis of chronic ischemic heart disease were taken from our hospital with patients from the clinic with laboratory tests and multidetector computed tomography (MDCT) performed. In total, there were 190 patients. Radiology reports and MDCT reports, clinical features, and values from the laboratory were obtained from the data system. The patients were divided into three groups according to the risk of coronary event, which was identified by coronary artery calcium score, age, and gender: low (105), medium (45), and high (40). The correlation between MPV and uric acid values was examined within these three groups. In addition, the patients with and without type 2 DM had the correlation with actual values examined. A p value <0.05 was considered statistically significant.Results: According to this study, the comparison of coronary artery calcium score and the coronary event risk of the group with MPV and uric acid values showed that there was no statistical significance. In the study, in the diabetic patient group, MPV, coronary artery calcium score, risk of coronary event, and plaque volume were significantly higher.Conclusion: Although coronary artery calcium score is seen as an independent risk factor for the prediction of coronary artery disease, in our study, there was no relation between MPV and uric acid values and coronary artery score, which indicates atherosclerosis in the coronary artery.