Secreted hCLCA1 is a signaling molecule that activates airway macrophages.

Secreted hCLCA1 is a signaling molecule that activates airway macrophages.

The CLCA gene family produces both secreted and membrane-associated proteins that modulate ion-channel function, drive mucus production and have a poorly understood pleiotropic effect on airway inflammation. The primary up-regulated human CLCA ortholog in airway inflammation is hCLCA1. Here we show...

Full description

Bibliographic Details
Main Authors: John C H Ching, Liubov Lobanova, Matthew E Loewen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861482?pdf=render

Similar Items

Similar Items