Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease
Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have sever...
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2020-07-01
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doaj-4e9c01ea2aa1432f9179704726ac8ed22020-11-25T03:29:03ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-07-01810.3389/fped.2020.00363556262Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell DiseaseRobert Spencer0Gerson Valencia Villeda1Koji Takeda2Erika B. Rosenzweig3Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York, NY, United StatesDivision of Pediatric Cardiology, Arnold Palmer Hospital for Children, Orlando, FL, United StatesDivision of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY, United StatesDivision of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York, NY, United StatesChronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have severe PH on routine screening echocardiography. The diagnosis was confirmed by CT, ventilation-perfusion scintigraphy, and right heart catheterization. The patient was medically managed until undergoing pulmonary thromboendarterectomy with resolution of his PH. This case highlights the need for pediatric providers to be aware of this underdiagnosed form of PH, particularly for patients at high risk.https://www.frontiersin.org/article/10.3389/fped.2020.00363/fullpediatric cardiologypulmonary hypertensionCTEPH—chronic thromboembolic pulmonary hypertensionsickle cell diseasehematology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Robert Spencer Gerson Valencia Villeda Koji Takeda Erika B. Rosenzweig |
spellingShingle |
Robert Spencer Gerson Valencia Villeda Koji Takeda Erika B. Rosenzweig Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease Frontiers in Pediatrics pediatric cardiology pulmonary hypertension CTEPH—chronic thromboembolic pulmonary hypertension sickle cell disease hematology |
author_facet |
Robert Spencer Gerson Valencia Villeda Koji Takeda Erika B. Rosenzweig |
author_sort |
Robert Spencer |
title |
Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease |
title_short |
Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease |
title_full |
Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease |
title_fullStr |
Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease |
title_full_unstemmed |
Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease |
title_sort |
chronic thromboembolic pulmonary hypertension in a child with sickle cell disease |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Pediatrics |
issn |
2296-2360 |
publishDate |
2020-07-01 |
description |
Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have severe PH on routine screening echocardiography. The diagnosis was confirmed by CT, ventilation-perfusion scintigraphy, and right heart catheterization. The patient was medically managed until undergoing pulmonary thromboendarterectomy with resolution of his PH. This case highlights the need for pediatric providers to be aware of this underdiagnosed form of PH, particularly for patients at high risk. |
topic |
pediatric cardiology pulmonary hypertension CTEPH—chronic thromboembolic pulmonary hypertension sickle cell disease hematology |
url |
https://www.frontiersin.org/article/10.3389/fped.2020.00363/full |
work_keys_str_mv |
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