Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products

Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products

Humans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summ...

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Bibliographic Details
Main Authors: Yuanying Yang, Shanshan Wei, Bikui Zhang, Wenqun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
environmental toxins
cadmium
arsenic
pesticides
cardiotoxicity
natural products
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.699193/full
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spelling doaj-4ea1115c52a3473084e4721806492d872021-07-08T07:32:59ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122021-07-011210.3389/fphar.2021.699193699193Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural ProductsYuanying Yang0Yuanying Yang1Shanshan Wei2Shanshan Wei3Bikui Zhang4Bikui Zhang5Wenqun Li6Wenqun Li7Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, ChinaInstitute of Clinical Pharmacy, Central South University, Changsha, ChinaDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, ChinaInstitute of Clinical Pharmacy, Central South University, Changsha, ChinaDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, ChinaInstitute of Clinical Pharmacy, Central South University, Changsha, ChinaDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, ChinaInstitute of Clinical Pharmacy, Central South University, Changsha, ChinaHumans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summarizes the main mechanisms of cardiotoxicity induced by environmental toxins (cadmium, arsenic and pesticides) and discusses the potential preventive effects of natural products. These findings will provide a theoretical basis and novel agents for the prevention and treatment of environmental toxins-induced cardiotoxicity. Furthermore, the limitations of current studies, future needs and priorities are discussed.https://www.frontiersin.org/articles/10.3389/fphar.2021.699193/fullenvironmental toxinscadmiumarsenicpesticidescardiotoxicitynatural products
collection DOAJ
language English
format Article
sources DOAJ
author Yuanying Yang
Yuanying Yang
Shanshan Wei
Shanshan Wei
Bikui Zhang
Bikui Zhang
Wenqun Li
Wenqun Li
spellingShingle Yuanying Yang
Yuanying Yang
Shanshan Wei
Shanshan Wei
Bikui Zhang
Bikui Zhang
Wenqun Li
Wenqun Li
Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
Frontiers in Pharmacology
environmental toxins
cadmium
arsenic
pesticides
cardiotoxicity
natural products
author_facet Yuanying Yang
Yuanying Yang
Shanshan Wei
Shanshan Wei
Bikui Zhang
Bikui Zhang
Wenqun Li
Wenqun Li
author_sort Yuanying Yang
title Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_short Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_full Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_fullStr Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_full_unstemmed Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products
title_sort recent progress in environmental toxins-induced cardiotoxicity and protective potential of natural products
publisher Frontiers Media S.A.
series Frontiers in Pharmacology
issn 1663-9812
publishDate 2021-07-01
description Humans are unconsciously exposed to environmental toxins including heavy metals as well as various pesticides, which have deleterious effects on human health. Accumulating studies pointed out that exposure to environmental toxins was associated with various cardiopathologic effects. This review summarizes the main mechanisms of cardiotoxicity induced by environmental toxins (cadmium, arsenic and pesticides) and discusses the potential preventive effects of natural products. These findings will provide a theoretical basis and novel agents for the prevention and treatment of environmental toxins-induced cardiotoxicity. Furthermore, the limitations of current studies, future needs and priorities are discussed.
topic environmental toxins
cadmium
arsenic
pesticides
cardiotoxicity
natural products
url https://www.frontiersin.org/articles/10.3389/fphar.2021.699193/full
work_keys_str_mv AT yuanyingyang recentprogressinenvironmentaltoxinsinducedcardiotoxicityandprotectivepotentialofnaturalproducts
AT yuanyingyang recentprogressinenvironmentaltoxinsinducedcardiotoxicityandprotectivepotentialofnaturalproducts
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AT shanshanwei recentprogressinenvironmentaltoxinsinducedcardiotoxicityandprotectivepotentialofnaturalproducts
AT bikuizhang recentprogressinenvironmentaltoxinsinducedcardiotoxicityandprotectivepotentialofnaturalproducts
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