Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery?
OBJECTIVE: Pulmonary embolism (PE) is an important complication of major orthopedic surgery. The aim of this study was to evaluate the incidence of venous thromboembolism (VTE) and factors influencing the development of VTE in patients undergoing major orthopedic surgery in a university hospital....
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Sociedade Brasileira de Pneumologia e Tisiologia
2013-06-01
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doaj-4ea6bed2a4af4544a758bf2aa700560d2020-11-25T00:16:47ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-37562013-06-0139328028610.1590/S1806-37132013000300004S1806-37132013000300280Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery?Evrim Eylem AkpinarDerya HosgunBurak AkanCan AtesMeral GulhanOBJECTIVE: Pulmonary embolism (PE) is an important complication of major orthopedic surgery. The aim of this study was to evaluate the incidence of venous thromboembolism (VTE) and factors influencing the development of VTE in patients undergoing major orthopedic surgery in a university hospital. METHODS: Patients who underwent major orthopedic surgery (hip arthroplasty, knee arthroplasty, or femur fracture repair) between February of 2006 and June of 2012 were retrospectively included in the study. The incidences of PE and deep vein thrombosis (DVT) were evaluated, as were the factors influencing their development, such as type of operation, age, and comorbidities. RESULTS: We reviewed the medical records of 1,306 patients. The proportions of knee arthroplasty, hip arthroplasty, and femur fracture repair were 63.4%, 29.9%, and 6.7%, respectively. The cumulative incidence of PE and DVT in patients undergoing major orthopedic surgery was 1.99% and 2.22%, respectively. Most of the patients presented with PE and DVT (61.5% and 72.4%, respectively) within the first 72 h after surgery. Patients undergoing femur fracture repair, those aged ≥ 65 years, and bedridden patients were at a higher risk for developing VTE. CONCLUSIONS: Our results show that VTE was a significant complication of major orthopedic surgery, despite the use of thromboprophylaxis. Clinicians should be aware of VTE, especially during the perioperative period and in bedridden, elderly patients (≥ 65 years of age).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000300280&lng=en&tlng=enOrtopediaEmbolia pulmonarTrombose venosa |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Evrim Eylem Akpinar Derya Hosgun Burak Akan Can Ates Meral Gulhan |
spellingShingle |
Evrim Eylem Akpinar Derya Hosgun Burak Akan Can Ates Meral Gulhan Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? Jornal Brasileiro de Pneumologia Ortopedia Embolia pulmonar Trombose venosa |
author_facet |
Evrim Eylem Akpinar Derya Hosgun Burak Akan Can Ates Meral Gulhan |
author_sort |
Evrim Eylem Akpinar |
title |
Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
title_short |
Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
title_full |
Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
title_fullStr |
Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
title_full_unstemmed |
Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
title_sort |
does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery? |
publisher |
Sociedade Brasileira de Pneumologia e Tisiologia |
series |
Jornal Brasileiro de Pneumologia |
issn |
1806-3756 |
publishDate |
2013-06-01 |
description |
OBJECTIVE: Pulmonary embolism (PE) is an important complication of major orthopedic surgery. The aim of this study was to evaluate the incidence of venous thromboembolism (VTE) and factors influencing the development of VTE in patients undergoing major orthopedic surgery in a university hospital. METHODS: Patients who underwent major orthopedic surgery (hip arthroplasty, knee arthroplasty, or femur fracture repair) between February of 2006 and June of 2012 were retrospectively included in the study. The incidences of PE and deep vein thrombosis (DVT) were evaluated, as were the factors influencing their development, such as type of operation, age, and comorbidities. RESULTS: We reviewed the medical records of 1,306 patients. The proportions of knee arthroplasty, hip arthroplasty, and femur fracture repair were 63.4%, 29.9%, and 6.7%, respectively. The cumulative incidence of PE and DVT in patients undergoing major orthopedic surgery was 1.99% and 2.22%, respectively. Most of the patients presented with PE and DVT (61.5% and 72.4%, respectively) within the first 72 h after surgery. Patients undergoing femur fracture repair, those aged ≥ 65 years, and bedridden patients were at a higher risk for developing VTE. CONCLUSIONS: Our results show that VTE was a significant complication of major orthopedic surgery, despite the use of thromboprophylaxis. Clinicians should be aware of VTE, especially during the perioperative period and in bedridden, elderly patients (≥ 65 years of age). |
topic |
Ortopedia Embolia pulmonar Trombose venosa |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000300280&lng=en&tlng=en |
work_keys_str_mv |
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