Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study.
We aimed to calculate 3-year incidence of multimorbidity, defined as the development of two or more chronic diseases in a population of older people free from multimorbidity at baseline. Secondly, we aimed to identify predictors of incident multimorbidity amongst life-style related indicators, medic...
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doaj-4eb4c71c42fc47cf878c5778bc670efa2020-11-24T21:32:00ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0197e10312010.1371/journal.pone.0103120Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study.René MelisAlessandra MarengoniSara AnglemanLaura FratiglioniWe aimed to calculate 3-year incidence of multimorbidity, defined as the development of two or more chronic diseases in a population of older people free from multimorbidity at baseline. Secondly, we aimed to identify predictors of incident multimorbidity amongst life-style related indicators, medical conditions and biomarkers.Data were gathered from 418 participants in the first follow up of the Kungsholmen Project (Stockholm, Sweden, 1991-1993, 78+ years old) who were not affected by multimorbidity (149 had none disease and 269 one disease), including a social interview, a neuropsychological battery and a medical examination.After 3 years, 33.6% of participants who were without disease and 66.4% of those with one disease at baseline, developed multimorbidity: the incidence rate was 12.6 per 100 person-years (95% CI: 9.2-16.7) and 32.9 per 100 person-years (95% CI: 28.1-38.3), respectively. After adjustments, worse cognitive function (OR, 95% CI, for 1 point lower Mini-Mental State Examination: 1.22, 1.00-1.48) was associated with increased risk of multimorbidity among subjects with no disease at baseline. Higher age was the only predictor of multimorbidity in persons with one disease at baseline.Multimorbidity has a high incidence at old age. Mental health-related symptoms are likely predictors of multimorbidity, suggesting a strong impact of mental disorders on the health of older people.http://europepmc.org/articles/PMC4109993?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
René Melis Alessandra Marengoni Sara Angleman Laura Fratiglioni |
spellingShingle |
René Melis Alessandra Marengoni Sara Angleman Laura Fratiglioni Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. PLoS ONE |
author_facet |
René Melis Alessandra Marengoni Sara Angleman Laura Fratiglioni |
author_sort |
René Melis |
title |
Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
title_short |
Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
title_full |
Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
title_fullStr |
Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
title_full_unstemmed |
Incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
title_sort |
incidence and predictors of multimorbidity in the elderly: a population-based longitudinal study. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2014-01-01 |
description |
We aimed to calculate 3-year incidence of multimorbidity, defined as the development of two or more chronic diseases in a population of older people free from multimorbidity at baseline. Secondly, we aimed to identify predictors of incident multimorbidity amongst life-style related indicators, medical conditions and biomarkers.Data were gathered from 418 participants in the first follow up of the Kungsholmen Project (Stockholm, Sweden, 1991-1993, 78+ years old) who were not affected by multimorbidity (149 had none disease and 269 one disease), including a social interview, a neuropsychological battery and a medical examination.After 3 years, 33.6% of participants who were without disease and 66.4% of those with one disease at baseline, developed multimorbidity: the incidence rate was 12.6 per 100 person-years (95% CI: 9.2-16.7) and 32.9 per 100 person-years (95% CI: 28.1-38.3), respectively. After adjustments, worse cognitive function (OR, 95% CI, for 1 point lower Mini-Mental State Examination: 1.22, 1.00-1.48) was associated with increased risk of multimorbidity among subjects with no disease at baseline. Higher age was the only predictor of multimorbidity in persons with one disease at baseline.Multimorbidity has a high incidence at old age. Mental health-related symptoms are likely predictors of multimorbidity, suggesting a strong impact of mental disorders on the health of older people. |
url |
http://europepmc.org/articles/PMC4109993?pdf=render |
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