Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells

Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells

Background. In this study the effect of histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) on the energetic status and cardiomyogenic differentiation of human healthy and dilated myocardium-derived mesenchymal stromal cells (hmMSC) have been investigated. Methods. The hmMSC...

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Bibliographic Details
Main Authors: Rokas Miksiunas, Kestutis Rucinskas, Vilius Janusauskas, Siegfried Labeit, Daiva Bironaite
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
histone deacetylase inhibitors
dilated cardiomyopathy
cardiomyogenic differentiation
primary mesenchymal cells
Online Access:https://www.mdpi.com/1422-0067/21/14/4845

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