Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human disease
Bibliographic Details
Main Authors: |
Jiangping He,
Isaac A. Babarinde,
Li Sun,
Shuyang Xu,
Ruhai Chen,
Junjie Shi,
Yuanjie Wei,
Yuhao Li,
Gang Ma,
Qiang Zhuang,
Andrew P. Hutchins,
Jiekai Chen |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-021-21808-x
|