HISTOSPECTROPHOTOMETRICAL AND IMMUNOHISTOCHEMISTRICAL RESEARCH OF RENAL INTRATUBULAR NEOPLASIA IN PERITUMOUROUS ZONE OF A RENAL CARCINOMA

HISTOSPECTROPHOTOMETRICAL AND IMMUNOHISTOCHEMISTRICAL RESEARCH OF RENAL INTRATUBULAR NEOPLASIA IN PERITUMOUROUS ZONE OF A RENAL CARCINOMA

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In this work displays renal intratubular neoplasia (RIN) in peritumourous zone of a renal carcinoma have been studied. The object of our work, are the operative materials of 42 patients. Middle age of patients has made 57,4 ± 1,4 year. Men was 25, women — 17. Characteristic of tubular epithelium in...

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Bibliographic Details
Main Authors: T. M. Cherdantseva, I. P. Bobrov, V. V. Klimachev, V. M. Brjuhanov, A. F. Lazarev, A. M. Avdalyan, V. Ya. Gervald, E. I. Sechenev
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Onkourologiâ
Subjects:
renal carcinoma
peritumourous zone
renal intratubular neoplasia
Online Access:https://oncourology.abvpress.ru/oncur/article/view/311
Description
Summary:In this work displays renal intratubular neoplasia (RIN) in peritumourous zone of a renal carcinoma have been studied. The object of our work, are the operative materials of 42 patients. Middle age of patients has made 57,4 ± 1,4 year. Men was 25, women — 17. Characteristic of tubular epithelium in PZ a renal carcinoma have been studied morphofunctional by means of histological, histospectrophotometrical and immunohistochemistrical methods. It is shown, that in PZ tumors of a high degree displays, of RIN much more often, than in tumors of low degree anaplasia. In tumors of a high degree anaplasia in tubular epithelium PZ registered increasing of nucleus, ploidy and expression of AgNORs, Ki-67, p53 and bcl-2. The presence of displays RIN in tubular epithelium PZ at a renal carcinoma should be considered at surgery operations.
ISSN:1726-9776
1996-1812

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