Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis.
The role of proteins often changes during evolution, but we do not know how cells adapt when a protein is asked to participate in a different biological function. We forced the budding yeast, Saccharomyces cerevisiae, to use the meiosis-specific kleisin, recombination 8 (Rec8), during the mitotic ce...
Main Authors: | Yu-Ying Phoebe Hsieh, Vasso Makrantoni, Daniel Robertson, Adèle L Marston, Andrew W Murray |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-03-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000635 |
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