Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation

Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation

Abstract A prothrombotic state is a typical feature of type 2 diabetes mellitus (T2DM). Apart from increased platelet reactivity, endothelial dysfunction, hyperfibrinogenemia, and hypofibrinolysis are observed in T2DM. A variety of poorly elucidated mechanisms behind impaired fibrinolysis in this di...

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Bibliographic Details
Main Authors: Agata Hanna Bryk-Wiązania, Anetta Undas
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cardiovascular Diabetology
Subjects:
Type 2 diabetes
Fibrinolysis
Cardiovascular mortality
Online Access:https://doi.org/10.1186/s12933-021-01372-w

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