Update on antiphospholipid antibody syndrome
Summary Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antiphospholipid antibodies (aPL) associated with thrombosis and/or pregnancy morbidity. Most APS events are directly related to thrombotic events, which may affect small, medium or large vessels. Other clinical featur...
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doaj-4f0ed6bdf4d8498f990e33a5b06ec2f12020-11-24T22:38:18ZengAssociação Médica BrasileiraRevista da Associação Médica Brasileira1806-9282631199499910.1590/1806-9282.63.11.994S0104-42302017001100994Update on antiphospholipid antibody syndromeMichelle Remião Ugolini LopesAdriana DanowskiAndreas FunkeJozelia RêgoRoger LevyDanieli Castro Oliveira de AndradeSummary Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antiphospholipid antibodies (aPL) associated with thrombosis and/or pregnancy morbidity. Most APS events are directly related to thrombotic events, which may affect small, medium or large vessels. Other clinical features like thrombocytopenia, nephropathy, cardiac valve disease, cognitive dysfunction and skin ulcers (called non-criteria manifestations) add significant morbidity to this syndrome and represent clinical situations that are challenging. APS was initially described in patients with systemic lupus erythematosus (SLE) but it can occur in patients without any other autoimmune disease. Despite the autoimmune nature of this syndrome, APS treatment is still based on anticoagulation and antiplatelet therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017001100994&lng=en&tlng=enantiphospholipid syndromeanticoagulantsthrombosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Michelle Remião Ugolini Lopes Adriana Danowski Andreas Funke Jozelia Rêgo Roger Levy Danieli Castro Oliveira de Andrade |
spellingShingle |
Michelle Remião Ugolini Lopes Adriana Danowski Andreas Funke Jozelia Rêgo Roger Levy Danieli Castro Oliveira de Andrade Update on antiphospholipid antibody syndrome Revista da Associação Médica Brasileira antiphospholipid syndrome anticoagulants thrombosis |
author_facet |
Michelle Remião Ugolini Lopes Adriana Danowski Andreas Funke Jozelia Rêgo Roger Levy Danieli Castro Oliveira de Andrade |
author_sort |
Michelle Remião Ugolini Lopes |
title |
Update on antiphospholipid antibody syndrome |
title_short |
Update on antiphospholipid antibody syndrome |
title_full |
Update on antiphospholipid antibody syndrome |
title_fullStr |
Update on antiphospholipid antibody syndrome |
title_full_unstemmed |
Update on antiphospholipid antibody syndrome |
title_sort |
update on antiphospholipid antibody syndrome |
publisher |
Associação Médica Brasileira |
series |
Revista da Associação Médica Brasileira |
issn |
1806-9282 |
description |
Summary Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antiphospholipid antibodies (aPL) associated with thrombosis and/or pregnancy morbidity. Most APS events are directly related to thrombotic events, which may affect small, medium or large vessels. Other clinical features like thrombocytopenia, nephropathy, cardiac valve disease, cognitive dysfunction and skin ulcers (called non-criteria manifestations) add significant morbidity to this syndrome and represent clinical situations that are challenging. APS was initially described in patients with systemic lupus erythematosus (SLE) but it can occur in patients without any other autoimmune disease. Despite the autoimmune nature of this syndrome, APS treatment is still based on anticoagulation and antiplatelet therapy. |
topic |
antiphospholipid syndrome anticoagulants thrombosis |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017001100994&lng=en&tlng=en |
work_keys_str_mv |
AT michelleremiaougolinilopes updateonantiphospholipidantibodysyndrome AT adrianadanowski updateonantiphospholipidantibodysyndrome AT andreasfunke updateonantiphospholipidantibodysyndrome AT jozeliarego updateonantiphospholipidantibodysyndrome AT rogerlevy updateonantiphospholipidantibodysyndrome AT danielicastrooliveiradeandrade updateonantiphospholipidantibodysyndrome |
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