Oncostatin M Modulation of Lipid Storage

Oncostatin M Modulation of Lipid Storage

Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological...

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Bibliographic Details
Main Authors: Carrie M. Elks, Jacqueline M. Stephens
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Biology
Subjects:
oncostatin M
gp130 cytokines
adipocyte
obesity
adipose tissue
Online Access:http://www.mdpi.com/2079-7737/4/1/151
Description
Summary:Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.
ISSN:2079-7737

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