Oncostatin M Modulation of Lipid Storage

Oncostatin M Modulation of Lipid Storage

Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological...

Full description

Bibliographic Details
Main Authors: Carrie M. Elks, Jacqueline M. Stephens
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Biology
Subjects:
oncostatin M
gp130 cytokines
adipocyte
obesity
adipose tissue
Online Access:http://www.mdpi.com/2079-7737/4/1/151
id doaj-4f10d547e4f74aa794280f99f6847621
record_format Article
spelling doaj-4f10d547e4f74aa794280f99f68476212020-11-24T22:17:45ZengMDPI AGBiology2079-77372015-02-014115116010.3390/biology4010151biology4010151Oncostatin M Modulation of Lipid StorageCarrie M. Elks0Jacqueline M. Stephens1Adipocyte Biology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USAAdipocyte Biology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USAOncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.http://www.mdpi.com/2079-7737/4/1/151oncostatin Mgp130 cytokinesadipocyteobesityadipose tissue
collection DOAJ
language English
format Article
sources DOAJ
author Carrie M. Elks
Jacqueline M. Stephens
spellingShingle Carrie M. Elks
Jacqueline M. Stephens
Oncostatin M Modulation of Lipid Storage
Biology
oncostatin M
gp130 cytokines
adipocyte
obesity
adipose tissue
author_facet Carrie M. Elks
Jacqueline M. Stephens
author_sort Carrie M. Elks
title Oncostatin M Modulation of Lipid Storage
title_short Oncostatin M Modulation of Lipid Storage
title_full Oncostatin M Modulation of Lipid Storage
title_fullStr Oncostatin M Modulation of Lipid Storage
title_full_unstemmed Oncostatin M Modulation of Lipid Storage
title_sort oncostatin m modulation of lipid storage
publisher MDPI AG
series Biology
issn 2079-7737
publishDate 2015-02-01
description Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.
topic oncostatin M
gp130 cytokines
adipocyte
obesity
adipose tissue
url http://www.mdpi.com/2079-7737/4/1/151
work_keys_str_mv AT carriemelks oncostatinmmodulationoflipidstorage
AT jacquelinemstephens oncostatinmmodulationoflipidstorage
_version_ 1725784636949266432

Similar Items