Transplantation of an obesity-associated human gut microbiota to mice induces vascular dysfunction and glucose intolerance

Transplantation of an obesity-associated human gut microbiota to mice induces vascular dysfunction and glucose intolerance

Recent preclinical data suggest that alterations in the gut microbiota may be an important factor linking obesity to vascular dysfunction, an early sign of cardiovascular disease. The purpose of this study was to begin translation of these preclinical data by examining whether vascular phenotypes in...

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Bibliographic Details
Main Authors: S. Raj J. Trikha, Dustin M. Lee, Kayl E. Ecton, Scott D. Wrigley, Allegra R. Vazquez, Nicole S. Litwin, Keely N. Thomas, Yuren Wei, Micah L. Battson, Sarah A. Johnson, Kristine A. Kuhn, Sean P. Colgan, Christopher L. Gentile, Tiffany L. Weir
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Gut Microbes
Subjects:
vascular function
pulse wave velocity
endothelial function
obesity
microbiota
cardiovascular disease
Online Access:http://dx.doi.org/10.1080/19490976.2021.1940791

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