Give it AGO: The search for miRNA-Argonaute sorting signals in Arabidopsis thaliana indicates a relevance of sequence positions other than the 5’-position alone.

Give it AGO: The search for miRNA-Argonaute sorting signals in Arabidopsis thaliana indicates a relevance of sequence positions other than the 5’-position alone.

The specific recognition of miRNAs by Argonaute (AGO) proteins, the effector proteins of the RNA-induced silencing complex, constitutes the final step of the biogenesis of miRNAs and is crucial for their target interaction. In the genome of Arabidopsis thaliana (Ath), 10 different AGO proteins are e...

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Bibliographic Details
Main Authors: Christoph J Thieme, Christian eSchudoma, Patrick eMay, Dirk eWalther
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Plant Science
Subjects:
Argonaute Proteins
machine learning
miRNA
Arabidopsis thaliana
mutual information
sorting
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2012.00272/full

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