Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study
Cardiovascular disease (CVD) is the leading cause of death worldwide. There is a consistent inverse relationship between fruit intake with CVD events and mortality in cross-sectional and prospective observational studies, but the relationship of fruit intake with measurements of atherosclerosis in h...
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doaj-4f40c5fd0aac4e74a3418530b57b2d082020-11-24T23:55:14ZengMDPI AGNutrients2072-66432016-03-018315910.3390/nu8030159nu8030159Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort StudyNicola P. Bondonno0Joshua R. Lewis1Richard L. Prince2Wai H. Lim3Germaine Wong4John T. Schousboe5Richard J. Woodman6Douglas P. Kiel7Catherine P. Bondonno8Natalie C. Ward9Kevin D. Croft10Jonathan M. Hodgson11Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth 6000, Western Australia, AustraliaCentre for Kidney Research, Children’s Hospital at Westmead, Sydney 2145, New South Wales, AustraliaSir Charles Gairdner Hospital Unit, School of Medicine and Pharmacology, University of Western Australia, Perth 6009, Western Australia, AustraliaSir Charles Gairdner Hospital Unit, School of Medicine and Pharmacology, University of Western Australia, Perth 6009, Western Australia, AustraliaCentre for Kidney Research, Children’s Hospital at Westmead, Sydney 2145, New South Wales, AustraliaPark Nicollet Osteoporosis Centre and HealthPartners Institute, HealthPartners, Minneapolis, MN 55416, USACentre for Epidemiology and Biostatistics, School of Public Health, Flinders University of South Australia, Adelaide 5042, South Australia, AustraliaInstitute for Aging Research, Hebrew Senior Life, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA 02215, USARoyal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth 6000, Western Australia, AustraliaRoyal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth 6000, Western Australia, AustraliaRoyal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth 6000, Western Australia, AustraliaRoyal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth 6000, Western Australia, AustraliaCardiovascular disease (CVD) is the leading cause of death worldwide. There is a consistent inverse relationship between fruit intake with CVD events and mortality in cross-sectional and prospective observational studies, but the relationship of fruit intake with measurements of atherosclerosis in humans is less clear. Nutritional effects on abdominal aortic calcification (AAC), a marker for subclinical intimal and medial atherosclerotic vascular disease, have not been studied previously. The aim of this study was to examine the cross-sectional relationship of total and individual fruit (apple, pear, orange and other citrus, and banana) intake with AAC, scored between 0 and 24. The current study assessed baseline data for a cohort of 1052 women over 70 years of age who completed both a food frequency questionnaire assessing fruit intake, and underwent AAC measurement using dual energy X-ray absorptiometry. AAC scores were significantly negatively correlated with total fruit and apple intakes (p < 0.05), but not with pear, orange or banana intakes (p > 0.25). In multivariable-adjusted logistic regression, each standard deviation (SD; 50 g/day) increase in apple intake was associated with a 24% lower odds of having severe AAC (AAC score >5) (odd ratio OR): 0.76 (0.62, 0.93), p = 0.009). Total and other individual fruit intake were not associated with increased odds of having severe AAC. Apple but not total or other fruit intake is independently negatively associated with AAC in older women.http://www.mdpi.com/2072-6643/8/3/159applesfruitabdominal aortic calcificationatherosclerosiscardiovascular disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nicola P. Bondonno Joshua R. Lewis Richard L. Prince Wai H. Lim Germaine Wong John T. Schousboe Richard J. Woodman Douglas P. Kiel Catherine P. Bondonno Natalie C. Ward Kevin D. Croft Jonathan M. Hodgson |
spellingShingle |
Nicola P. Bondonno Joshua R. Lewis Richard L. Prince Wai H. Lim Germaine Wong John T. Schousboe Richard J. Woodman Douglas P. Kiel Catherine P. Bondonno Natalie C. Ward Kevin D. Croft Jonathan M. Hodgson Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study Nutrients apples fruit abdominal aortic calcification atherosclerosis cardiovascular disease |
author_facet |
Nicola P. Bondonno Joshua R. Lewis Richard L. Prince Wai H. Lim Germaine Wong John T. Schousboe Richard J. Woodman Douglas P. Kiel Catherine P. Bondonno Natalie C. Ward Kevin D. Croft Jonathan M. Hodgson |
author_sort |
Nicola P. Bondonno |
title |
Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study |
title_short |
Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study |
title_full |
Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study |
title_fullStr |
Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study |
title_full_unstemmed |
Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study |
title_sort |
fruit intake and abdominal aortic calcification in elderly women: a prospective cohort study |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2016-03-01 |
description |
Cardiovascular disease (CVD) is the leading cause of death worldwide. There is a consistent inverse relationship between fruit intake with CVD events and mortality in cross-sectional and prospective observational studies, but the relationship of fruit intake with measurements of atherosclerosis in humans is less clear. Nutritional effects on abdominal aortic calcification (AAC), a marker for subclinical intimal and medial atherosclerotic vascular disease, have not been studied previously. The aim of this study was to examine the cross-sectional relationship of total and individual fruit (apple, pear, orange and other citrus, and banana) intake with AAC, scored between 0 and 24. The current study assessed baseline data for a cohort of 1052 women over 70 years of age who completed both a food frequency questionnaire assessing fruit intake, and underwent AAC measurement using dual energy X-ray absorptiometry. AAC scores were significantly negatively correlated with total fruit and apple intakes (p < 0.05), but not with pear, orange or banana intakes (p > 0.25). In multivariable-adjusted logistic regression, each standard deviation (SD; 50 g/day) increase in apple intake was associated with a 24% lower odds of having severe AAC (AAC score >5) (odd ratio OR): 0.76 (0.62, 0.93), p = 0.009). Total and other individual fruit intake were not associated with increased odds of having severe AAC. Apple but not total or other fruit intake is independently negatively associated with AAC in older women. |
topic |
apples fruit abdominal aortic calcification atherosclerosis cardiovascular disease |
url |
http://www.mdpi.com/2072-6643/8/3/159 |
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