Circulating tight-junction proteins are potential biomarkers for blood–brain barrier function in a model of neonatal hypoxic/ischemic brain injury

Circulating tight-junction proteins are potential biomarkers for blood–brain barrier function in a model of neonatal hypoxic/ischemic brain injury

Abstract Background Neonatal encephalopathy often leads to lifelong disabilities with limited treatments currently available. The brain vasculature is an important factor in many neonatal neurological disorders but there is a lack of diagnostic tools to evaluate the brain vascular dysfunction of neo...

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Bibliographic Details
Main Authors: E. Axel Andersson, Carina Mallard, C. Joakim Ek
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Fluids and Barriers of the CNS
Subjects:
Biomarkers
Blood–brain barrier
Hypoxia/ischemia
Neonatal
Tight-junctions
Online Access:https://doi.org/10.1186/s12987-021-00240-9

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