Metabolism of methyl elaidate*

Methyl elaidate-l-C14 was fed to fat-deficient guinea pigs. Very little incorporation of the radioactivity was found in the glycerides or phospholipids under these conditions. Methyl ester seemed to have been absorbed without complete hydrolysis and deposited in body tissues as the methyl ester. Int...

Full description

Bibliographic Details
Main Authors: G.A. Dhopeshwarkar, James F. Mead
Format: Article
Language:English
Published: Elsevier 1962-04-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520404341
id doaj-4f52cdd168ab4d61ae3ac9abe70f153d
record_format Article
spelling doaj-4f52cdd168ab4d61ae3ac9abe70f153d2021-04-23T06:13:06ZengElsevierJournal of Lipid Research0022-22751962-04-0132238242Metabolism of methyl elaidate*G.A. Dhopeshwarkar0James F. Mead1Department of Physiological Chemistry, School of Medicine, University of California, Los Angeles, CaliforniaDepartment of Physiological Chemistry, School of Medicine, University of California, Los Angeles, CaliforniaMethyl elaidate-l-C14 was fed to fat-deficient guinea pigs. Very little incorporation of the radioactivity was found in the glycerides or phospholipids under these conditions. Methyl ester seemed to have been absorbed without complete hydrolysis and deposited in body tissues as the methyl ester. Intestinal lipids from these animals showed the presence of unhydrolyzed free methyl esters even after a period of 4 hours. Percentage distribution of the radioactivity in the stearic acid isolated from these animals shows direct in vivo hydrogenation of elaidic acid to stearic acid.http://www.sciencedirect.com/science/article/pii/S0022227520404341
collection DOAJ
language English
format Article
sources DOAJ
author G.A. Dhopeshwarkar
James F. Mead
spellingShingle G.A. Dhopeshwarkar
James F. Mead
Metabolism of methyl elaidate*
Journal of Lipid Research
author_facet G.A. Dhopeshwarkar
James F. Mead
author_sort G.A. Dhopeshwarkar
title Metabolism of methyl elaidate*
title_short Metabolism of methyl elaidate*
title_full Metabolism of methyl elaidate*
title_fullStr Metabolism of methyl elaidate*
title_full_unstemmed Metabolism of methyl elaidate*
title_sort metabolism of methyl elaidate*
publisher Elsevier
series Journal of Lipid Research
issn 0022-2275
publishDate 1962-04-01
description Methyl elaidate-l-C14 was fed to fat-deficient guinea pigs. Very little incorporation of the radioactivity was found in the glycerides or phospholipids under these conditions. Methyl ester seemed to have been absorbed without complete hydrolysis and deposited in body tissues as the methyl ester. Intestinal lipids from these animals showed the presence of unhydrolyzed free methyl esters even after a period of 4 hours. Percentage distribution of the radioactivity in the stearic acid isolated from these animals shows direct in vivo hydrogenation of elaidic acid to stearic acid.
url http://www.sciencedirect.com/science/article/pii/S0022227520404341
work_keys_str_mv AT gadhopeshwarkar metabolismofmethylelaidate
AT jamesfmead metabolismofmethylelaidate
_version_ 1721513204970946560