Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups
This article presents a review on population genetics of Latvians, which alongside Lithuanians are the two extant Baltic speaking populations. The article provides a description of genome-wide single nucleotide polymorphism (SNP) data and contains a comparative analysis of the results of studies per...
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doaj-4f558cf66f60411cb342424345625d442021-09-05T14:01:13ZengSciendoProceedings of the Latvian Academy of Sciences. Section B, Natural Sciences1407-009X2018-06-0172313115110.2478/prolas-2018-0025prolas-2018-0025Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic GroupsKrūmiņa Astrīda0Pliss Liāna1Zariņa Gunita2Puzuka Agrita3Zariņa Agnese4Lāce Baiba5Elferts Didzis6Khrunin Andrey7Limborska Svetlana8Kloviņš Jānis9Gailīte Piekuse Linda10Scientific Laboratory of Molecular Genetics, Rīga Stradiņš University, Rīga, 16 Dzirciema Str., LV-1007, LatviaLatvian Biomedical Research and Study Centre, 1 Rātsupītes Str., LV-1067, Rīga, LatviaInstitute of Latvian History, University of Latvia, 4 Kalpaka Blvd., Rīga, LV-1050, LatviaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, Rīga, 16 Dzirciema Str., LV-1007, LatviaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, Rīga, 16 Dzirciema Str., LV-1007, LatviaLatvian Biomedical Research and Study Centre, 1 Rātsupītes Str., LV-1067, Rīga, LatviaFaculty of Biology, University of Latvia, 1 Jelgavas Str., LV-1004, Rīga, LatviaInstitute of Molecular Genetics, Russian Academy of Sciences, 2 Kurchatov Sq., Moscow, 123182, RussiaInstitute of Molecular Genetics, Russian Academy of Sciences, 2 Kurchatov Sq., Moscow, 123182, RussiaLatvian Biomedical Research and Study Centre, 1 Rātsupītes Str., LV-1067, Rīga, LatviaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, Rīga, 16 Dzirciema Str., LV-1007, LatviaThis article presents a review on population genetics of Latvians, which alongside Lithuanians are the two extant Baltic speaking populations. The article provides a description of genome-wide single nucleotide polymorphism (SNP) data and contains a comparative analysis of the results of studies performed on classical autosomal genetic markers, mitochondrial DNA (mtDNA) and the non-recombining part of the Y chromosome (NRY), with data on neighbouring populations. The study also covers data of recently performed ancient DNA (aDNA) studies carried out on samples from the territory of today’s Latvia. The results of population genetic studies have shown a mixture of eastern and western genetic traits in present-day Latvians with only small differences between Latvian subpopulations. Studies of the Baltic “tribal gene” LWb, as well as the gene’s SERPINA1 allele PIZ have indicated the presence of a considerable Baltic admixture in the neighbouring Finno-Ugric and Slavic populations. Although mtDNA analyses have shown that Latvians genetically in general belong to the same common gene pool as most of the Europeans, the Y-chromosomal lineage composition suggests that they are most similar to Northern and Eastern European populations of Lithuanians, Estonians, and Eastern-Slavic populations, which are ethnogenetically closest to them. The analysis of aDNA from the Early and Middle Neolithic did not present any genomic evidence of gene-flow from Central European farmers or any mitochondrial or Y-chromosomal haplogroups that are typical for them in the hunter-gatherers from the territory of today’s Latvia and Lithuania.https://doi.org/10.2478/prolas-2018-0025population geneticslatviansautosomesmitochondrial dnay chromosome |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Krūmiņa Astrīda Pliss Liāna Zariņa Gunita Puzuka Agrita Zariņa Agnese Lāce Baiba Elferts Didzis Khrunin Andrey Limborska Svetlana Kloviņš Jānis Gailīte Piekuse Linda |
spellingShingle |
Krūmiņa Astrīda Pliss Liāna Zariņa Gunita Puzuka Agrita Zariņa Agnese Lāce Baiba Elferts Didzis Khrunin Andrey Limborska Svetlana Kloviņš Jānis Gailīte Piekuse Linda Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups Proceedings of the Latvian Academy of Sciences. Section B, Natural Sciences population genetics latvians autosomes mitochondrial dna y chromosome |
author_facet |
Krūmiņa Astrīda Pliss Liāna Zariņa Gunita Puzuka Agrita Zariņa Agnese Lāce Baiba Elferts Didzis Khrunin Andrey Limborska Svetlana Kloviņš Jānis Gailīte Piekuse Linda |
author_sort |
Krūmiņa Astrīda |
title |
Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups |
title_short |
Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups |
title_full |
Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups |
title_fullStr |
Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups |
title_full_unstemmed |
Population Genetics of Latvians in the Context of Admixture between North-Eastern European Ethnic Groups |
title_sort |
population genetics of latvians in the context of admixture between north-eastern european ethnic groups |
publisher |
Sciendo |
series |
Proceedings of the Latvian Academy of Sciences. Section B, Natural Sciences |
issn |
1407-009X |
publishDate |
2018-06-01 |
description |
This article presents a review on population genetics of Latvians, which alongside Lithuanians are the two extant Baltic speaking populations. The article provides a description of genome-wide single nucleotide polymorphism (SNP) data and contains a comparative analysis of the results of studies performed on classical autosomal genetic markers, mitochondrial DNA (mtDNA) and the non-recombining part of the Y chromosome (NRY), with data on neighbouring populations. The study also covers data of recently performed ancient DNA (aDNA) studies carried out on samples from the territory of today’s Latvia. The results of population genetic studies have shown a mixture of eastern and western genetic traits in present-day Latvians with only small differences between Latvian subpopulations. Studies of the Baltic “tribal gene” LWb, as well as the gene’s SERPINA1 allele PIZ have indicated the presence of a considerable Baltic admixture in the neighbouring Finno-Ugric and Slavic populations. Although mtDNA analyses have shown that Latvians genetically in general belong to the same common gene pool as most of the Europeans, the Y-chromosomal lineage composition suggests that they are most similar to Northern and Eastern European populations of Lithuanians, Estonians, and Eastern-Slavic populations, which are ethnogenetically closest to them. The analysis of aDNA from the Early and Middle Neolithic did not present any genomic evidence of gene-flow from Central European farmers or any mitochondrial or Y-chromosomal haplogroups that are typical for them in the hunter-gatherers from the territory of today’s Latvia and Lithuania. |
topic |
population genetics latvians autosomes mitochondrial dna y chromosome |
url |
https://doi.org/10.2478/prolas-2018-0025 |
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