Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.

Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.

Porphyromonas gingivalis is a major periodontal pathogen that contains a variety of virulence factors. The antibody titer to P. gingivalis GroEL, a homologue of HSP60, is significantly higher in periodontitis patients than in healthy control subjects, suggesting that P. gingivalis GroEL is a potenti...

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Main Authors: Feng-Yen Lin, Fung-Ping Hsiao, Chun-Yao Huang, Chun-Ming Shih, Nai-Wen Tsao, Chien-Sung Tsai, Shue-Fen Yang, Nen-Chung Chang, Shan-Ling Hung, Yi-Wen Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4109931?pdf=render

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http://europepmc.org/articles/PMC4109931?pdf=render

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