Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.

Porphyromonas gingivalis is a major periodontal pathogen that contains a variety of virulence factors. The antibody titer to P. gingivalis GroEL, a homologue of HSP60, is significantly higher in periodontitis patients than in healthy control subjects, suggesting that P. gingivalis GroEL is a potenti...

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Main Authors: Feng-Yen Lin, Fung-Ping Hsiao, Chun-Yao Huang, Chun-Ming Shih, Nai-Wen Tsao, Chien-Sung Tsai, Shue-Fen Yang, Nen-Chung Chang, Shan-Ling Hung, Yi-Wen Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4109931?pdf=render

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