Post-translational modifications of CDK5 and their biological roles in cancer
Abstract Post-translational modifications (PTMs) of Cyclin-dependent kinase 5 (CDK5) have emerged as important regulatory mechanisms that modulate cancer development in patients. Though CDK5 is an atypical member of the cyclin-dependent kinase family, its aberrant expression links to cell proliferat...
Main Authors: | Gui-Bin Gao, Yue Sun, Run-Dong Fang, Ying Wang, Yang Wang, Qing-Yu He |
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Format: | Article |
Language: | English |
Published: |
Springer
2021-07-01
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Series: | Molecular Biomedicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43556-021-00029-0 |
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