Ginsenoside Rg3 Attenuates Lipopolysaccharide-Induced Acute Lung Injury via MerTK-Dependent Activation of the PI3K/AKT/mTOR Pathway
Acute lung injury (ALI) is a common clinical disease with high morbidity in both humans and animals. Ginsenoside Rg3, a type of traditional Chinese medicine extracted from ginseng, is widely used to cure many inflammation-related diseases. However, the specific molecular mechanism of the effects of...
Main Authors: | Jing Yang, Senyang Li, Luyao Wang, Fen Du, Xiaoliu Zhou, Qiqi Song, Junlong Zhao, Rui Fang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-08-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2018.00850/full |
Similar Items
-
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
by: Kayla V. Myers, et al.
Published: (2019-05-01) -
Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency
by: Deborah S. Lew, et al.
Published: (2020-07-01) -
Tim4- and MerTK-Mediated Engulfment of Apoptotic Cells by Mouse Resident Peritoneal Macrophages
by: Nishi, Chihiro
Published: (2016) -
Anti-Angiogenic Properties of Ginsenoside Rg3
by: Maryam Nakhjavani, et al.
Published: (2020-10-01) -
Expression of TAM-R in Human Immune Cells and Unique Regulatory Function of MerTK in IL-10 Production by Tolerogenic DC
by: Paul Giroud, et al.
Published: (2020-09-01)