Secreted factors from dental pulp stem cells improve Sjögren’s syndrome via regulatory T cell-mediated immunosuppression
Abstract Background Sjögren’s syndrome (SS) is a chronic autoimmune disease primarily characterized by inflammation in the salivary and lacrimal glands. Activated T cells contribute to disease pathogenesis by producing proinflammatory cytokines, which leads to a positive feedback loop establishment....
Main Authors: | Mayu Matsumura-Kawashima, Kenichi Ogata, Masafumi Moriyama, Yuka Murakami, Tatsuya Kawado, Seiji Nakamura |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-021-02236-6 |
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