Saponinas antifúngicas de Swartzia langsdorffii Antifungal saponins from Swartzia langsdorffii

Saponinas antifúngicas de Swartzia langsdorffii Antifungal saponins from Swartzia langsdorffii

<abstract language="eng">Chromatographic fractionation of the EtOH extract from the leaves of Swartzia langsdorffii afforded the pentacyclic triterpenes oleanolic acid and lupeol, and two saponins: oleanolic acid 3-sophoroside and the new ester 3-O-b-D-(6'-methyl)-glucopyranosyl...

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Bibliographic Details
Main Authors: Sara Regina de Marqui, Renata Brionízio Lemos, Luciana Ávila Santos, Ian Castro-Gamboa, Alberto José Cavalheiro, Vanderlan da Silva Bolzani, Dulce Helena Siqueira Silva, Liliana Scorzoni, Ana Maria Fusco-Almeida, Maria José Soares Mendes-Giannini, Maria Claudia Marx Young, Luce Maria Brandão Torres
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2008-01-01
Series:Química Nova
Subjects:
Swartzia langsdorffii
saponins
antifungal activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400023
Description
Summary:<abstract language="eng">Chromatographic fractionation of the EtOH extract from the leaves of Swartzia langsdorffii afforded the pentacyclic triterpenes oleanolic acid and lupeol, and two saponins: oleanolic acid 3-sophoroside and the new ester 3-O-b-D-(6'-methyl)-glucopyranosyl-28-O-b-D-glucopyranosyl-oleanate. Their structures were elucidated from spectral data, including 2D NMR and HRESIMS experiments. Antifungal activity of all isolated compounds was evaluated, using phytopathogens Cladosporium cladosporioides and C. sphaerospermum, and human pathogens Candida albicans, C. krusei, C. parapsilosis and Cryptococcus neoformans.
ISSN:0100-4042
1678-7064

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